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1: Med Hypotheses. 2009 Mar;72(3):333-7. Epub 2008 Nov 28.Click here to read Links

Low-dose naltrexone for disease prevention and quality of life.

Brown N, Panksepp J.

Department of Humanities and Social Sciences, Embry-Riddle Aeronautical University, Daytona Beach, FL 32114, United States. NPHbrown@aol.com

The use of low-dose naltrexone (LDN) for the treatment and prophylaxis of various bodily disorders is discussed. Accumulating evidence suggests that LDN can promote health supporting immune-modulation which may reduce various oncogenic and inflammatory autoimmune processes. Since LDN can upregulate endogenous opioid activity, it may also have a role in promoting stress resilience, exercise, social bonding, and emotional well-being, as well as amelioration of psychiatric problems such a autism and depression. It is proposed that LDN can be used effectively as a buffer for a large variety of bodily and mental ailments through its ability to beneficially modulate both the immune system and the brain neurochemistries that regulate positive affect.

PMID: 19041189 [PubMed - indexed for MEDLINE]

Patient Drug Information

  • Naltrexone (ReVia® )

    Naltrexone is used along with counseling and social support to help people who have stopped drinking alcohol and using street drugs continue to avoid drinking or using drugs. Naltrexone should not be used to treat people...

  • Source: AHFS Consumer Medication Information