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Eur J Nucl Med Mol Imaging. 2009 Apr;36(4):602-6. doi: 10.1007/s00259-008-0983-y. Epub 2008 Nov 27.

Constant ambient temperature of 24 degrees C significantly reduces FDG uptake by brown adipose tissue in children scanned during the winter.

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  • 1Department of Radiology, Division of Nuclear Medicine/PET, Children's Hospital Boston, Harvard Medical School, Boston, MA 02115, USA.



The aim of this study was to determine if warming patients prior to and during (18)F-FDG uptake by controlling the room temperature could decrease uptake by brown adipose tissue (BAT).


A group of 40 children underwent (18)F-FDG PET after being kept in the injection room at a constant temperature of 24 degrees C for half an hour before and 1 hour after intravenous tracer administration. The rate of uptake by BAT in this group was compared to the uptake in a control group of 45 patients who underwent PET when the injection room temperature was 21 degrees C.


Uptake by BAT occurred in 5% of studies in the temperature-controlled room compared to 31% of studies performed when the injection room temperature was 21 degrees C (p<0.002).


Maintaining room temperature at a constant 24 degrees C, half an hour prior to and during the period of FDG uptake significantly decreases accumulation of FDG in BAT in children.

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