Display Settings:

Format

Send to:

Choose Destination
See comment in PubMed Commons below
Semin Cell Dev Biol. 2009 Apr;20(2):231-9. doi: 10.1016/j.semcdb.2008.10.006. Epub 2008 Oct 17.

Rhomboids: 7 years of a new protease family.

Author information

  • MRC Laboratory of Molecular Biology, Hills Road, Cambridge CB2 0QH, UK. MF1@mrc-lmb.cam.ac.uk

Abstract

Drosophila Rhomboid-1 was discovered to be the first known intramembrane serine protease about 7 years ago. The study of the rhomboid-like family has since blossomed, and the purpose of this review is to take stock of where the field is, and how it may progress in the next few years. Three major themes are the increasing understanding of the biological roles of rhomboids, the detailed information we now have about their function and mechanism, and the promising leads they offer as medical targets.

PMID:
19022390
[PubMed - indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Elsevier Science
    Loading ...
    Write to the Help Desk