This article reports the results of a study carried out with 30 Mexican-origin immigrants in drug user treatment in the United States-Mexico Border city of El Paso, Texas during 2007. Qualitative, semi-structured interviews were implemented to assess the dynamic social and economic factors that affect the delivery and utilization of treatment services, with emphasis on the impact of recent immigration-related laws and policies. The research provides initial data for evidence-based intervention and reinforces the need for culturally and gender appropriate treatment services for poor immigrants and their families. The study's limitations are noted.