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Nucleic Acids Res. 2009 Jan;37(Database issue):D550-4. doi: 10.1093/nar/gkn859. Epub 2008 Nov 16.

Génolevures: protein families and synteny among complete hemiascomycetous yeast proteomes and genomes.

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  • 1LaBRI, Laboratoire Bordelais de Recherche en Informatique, UMR CNRS 5800, 33405 Talence cedex, France. david.sherman@labri.fr

Abstract

The Génolevures online database (http://cbi.labri.fr/Genolevures/ and http://genolevures.org/) provides exploratory tools and curated data sets relative to nine complete and seven partial genome sequences determined and manually annotated by the Génolevures Consortium, to facilitate comparative genomic studies of Hemiascomycete yeasts. The 2008 update to the Génolevures database provides four new genomes in complete (subtelomere to subtelomere) chromosome sequences, 50,000 protein-coding and tRNA genes, and in silico analyses for each gene element. A key element is a novel classification of conserved multi-species protein families and their use in detecting synteny, gene fusions and other aspects of genome remodeling in evolution. Our purpose is to release high-quality curated data from complete genomes, with a focus on the relations between genes, genomes and proteins.

PMID:
19015150
[PubMed - indexed for MEDLINE]
PMCID:
PMC2686504
Free PMC Article
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