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1: BMC Bioinformatics. 2008 Nov 15;9:482.Click here to read Click here to read Links

CellProfiler Analyst: data exploration and analysis software for complex image-based screens.

Jones TR, Kang IH, Wheeler DB, Lindquist RA, Papallo A, Sabatini DM, Golland P, Carpenter AE.

Imaging Platform, Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA. thouis@broad.mit.edu

BACKGROUND: Image-based screens can produce hundreds of measured features for each of hundreds of millions of individual cells in a single experiment. RESULTS: Here, we describe CellProfiler Analyst, open-source software for the interactive exploration and analysis of multidimensional data, particularly data from high-throughput, image-based experiments. CONCLUSION: The system enables interactive data exploration for image-based screens and automated scoring of complex phenotypes that require combinations of multiple measured features per cell.

PMID: 19014601 [PubMed - indexed for MEDLINE]

PMCID: PMC2614436