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    AIDS. 2008 Nov 30;22(18):2537-40.

    Silent cardiac dysfunction and exercise intolerance in HIV+ men receiving combined antiretroviral therapies.

    Thöni GJ, Schuster I, Walther G, Nottin S, Vinet A, Boccara F, Mauboussin JM, Rouanet I, Edérhy S, Dauzat M, Messner-Pellenc P, Obert P.

    Source

    EA 4278, Faculty of Sciences, Avignon, France. gilles.thoni@univ-montp1.fr

    Abstract

    Resting and exercise cardiac function, skeletal muscle oxygenation and whole-body aerobic exercise capacities were evaluated prospectively in cardiac symptom-free HIV men receiving antiretroviral therapies and in healthy controls matched for age, physical activity, smoking and body surface area. HIV patients showed resting cardiac dysfunction, altered cardiac responses to exercise and depressed exercise tolerance. Exercise stroke volume kinetics and muscle oxygenation were impaired in HIV patients, especially in those with resting diastolic dysfunction.

    PMID:
    19005278
    [PubMed - indexed for MEDLINE]

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