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Autism. 2008 Nov;12(6):627-44. doi: 10.1177/1362361308097116.

Sensitivity and specificity of the Modified Checklist for Autism in Toddlers and the Social Communication Questionnaire in preschoolers suspected of having pervasive developmental disorders.

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  • 1Ohio State University, Columbus, Ohio 43210-1257, USA.

Abstract

This study assessed the psychometric properties of the Modified Checklist for Autism in Toddlers (M-CHAT) and the Social Communication Questionnaire (SCQ) in a sample of preschool children referred for possible pervasive developmental disorders (PDDs). The sample consisted of 82 children between the ages of 18 and 70 months (54 with a PDD diagnosis and 28 with non-PDD diagnoses). M-CHAT scores were analyzed for 56 children aged 18-48 months old and SCQ scores were analyzed for 65 children aged 30-70 months old. Optimal sensitivity and specificity were achieved using the cutoff score of any three items on the M-CHAT and lowering the cutoff score of the SCQ. The diagnostic agreement of both instruments was also compared in an overlapping subsample of 39 children aged 30-48 months. Overall, the M-CHAT and SCQ appear to more accurately classify children with PDDs who have lower intellectual and adaptive functioning.

PMID:
19005032
[PubMed - indexed for MEDLINE]
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