Curr Biol. 2008 Nov 11;18(21):R1019-21.

Protein quality control: on IPODs and other JUNQ.

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Max-Delbrück-Center for Molecular Medicine, Robert-Rössle-Str.10, 13125 Berlin, Germany.

Abstract

The accumulation of misfolded cytosolic or aggregation-prone proteins leads to cellular stress. To protect the cell, damaged or aggregated proteins are actively sequestered in two newly discovered quality control compartments, JUNQ and IPOD, which are highly conserved in evolution.

PMID:: 19000801; [PubMed - indexed for MEDLINE]

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