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Curr Opin Cell Biol. 2008 Dec;20(6):694-8. doi: 10.1016/j.ceb.2008.10.003. Epub 2008 Nov 19.

Centrosome function during stem cell division: the devil is in the details.

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  • 1Cell Division Group, Institute for Research in Biomedicine (IRB-Barcelona), PCB, c/ Josep Samitier 1-5, Barcelona, Spain. gonzalez@irbbarcelona.org


Cell polarity is inherent to animal development and requires microtubules. In essentially all non-terminally differentiated somatic and male germ-line animal cells, microtubule organisation is governed by centrosomes. Animal development without centrosomes would therefore seem inconceivable. The claim of flies without centrosomes may appear to challenge this notion. Does it?

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