Display Settings:

Format

Send to:

Choose Destination
See comment in PubMed Commons below
Semin Cell Dev Biol. 2009 May;20(3):283-92. doi: 10.1016/j.semcdb.2008.10.004. Epub 2008 Nov 1.

Steroid signaling and temperature-dependent sex determination-Reviewing the evidence for early action of estrogen during ovarian determination in turtles.

Author information

  • 1Section of Integrative Biology, University of Texas, 2400 Speedway, Austin, TX 78712, United States.

Abstract

The developmental processes underlying gonadal differentiation are conserved across vertebrates, but the triggers initiating these trajectories are extremely variable. The red-eared slider turtle (Trachemys scripta elegans) exhibits temperature-dependent sex determination (TSD), a system where incubation temperature during a temperature-sensitive period of development determines offspring sex. However, gonadal sex is sensitive to both temperature and hormones during this period-particularly estrogen. We present a model for temperature-based differences in aromatase expression as a critical step in ovarian determination. Localized estrogen production facilitates ovarian development while inhibiting male-specific gene expression. At male-producing temperatures aromatase is not upregulated, thereby allowing testis development.

PMID:
18992835
[PubMed - indexed for MEDLINE]
PMCID:
PMC2695493
Free PMC Article

Images from this publication.See all images (6)Free text

Figure 1
Figure 2
Figure 3
Figure 4
Figure 5
Figure 6
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Elsevier Science Icon for PubMed Central
    Loading ...
    Write to the Help Desk