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    Nature. 1991 Jan 10;349(6305):117-27.

    The GTPase superfamily: conserved structure and molecular mechanism.

    Source

    Department of Pharmacology, University of California, San Francisco 94143-0450.

    Abstract

    GTPases are conserved molecular switches, built according to a common structural design. Rapidly accruing knowledge of individual GTPases--crystal structures, biochemical properties, or results of molecular genetic experiments--support and generate hypotheses relating structure to function in other members of the diverse family of GTPases.

    PMID:
    1898771
    [PubMed - indexed for MEDLINE]

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