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1: Nature. 1991 Jan 10;349(6305):117-27.Click here to read Links

The GTPase superfamily: conserved structure and molecular mechanism.

Department of Pharmacology, University of California, San Francisco 94143-0450.

GTPases are conserved molecular switches, built according to a common structural design. Rapidly accruing knowledge of individual GTPases--crystal structures, biochemical properties, or results of molecular genetic experiments--support and generate hypotheses relating structure to function in other members of the diverse family of GTPases.

PMID: 1898771 [PubMed - indexed for MEDLINE]