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Cell. 2008 Oct 31;135(3):391-5. doi: 10.1016/j.cell.2008.10.016.

Autism: many genes, common pathways?

Author information

  • Neurogenetics Program, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095, USA. dhg@ucla.edu

Abstract

Autism is a heterogeneous neurodevelopmental syndrome with a complex genetic etiology. It is still not clear whether autism comprises a vast collection of different disorders akin to intellectual disability or a few disorders sharing common aberrant pathways. Unifying principles among cases of autism are likely to be at the level of brain circuitry in addition to molecular pathways.

PMID:
18984147
[PubMed - indexed for MEDLINE]
PMCID:
PMC2756410
Free PMC Article

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