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N Y State Dent J. 2008 Aug-Sep;74(5):65-6.

Relationship between cholesterol and triglyceride blood values and periodontal parameters in patients of Mashhad health center.

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  • 1Department of Periodontology, Mashhad Dental School and Dental Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.


Although the causal link between periodontitis and cardiovascular disease is supported by some research and seems biologically plausible, it remains a controversial topic. Now evidence suggests that periodontitis, once established, provides a biological burden of endotoxin and inflammatory cytokines, which serve to initiate and exacerbate atherogenesis and thromboembolic events. The aim of this study was to evaluate the relationship between periodontitis and blood level cholesterol and triglyceride changes. Seventy-one patients took part in this study. For each patient, a blood sample was taken and levels of total cholesterol, triglyceride and glucose were measured; a periodontal examination, including probing depth and bleeding on probing was carried out. Statistical analysis of the results suggested that with increasing levels of total blood cholesterol, average probing depth and the percentage of pockets more than 4 mm also increased. Although there was a direct correlation between periodontal and the measured biochemical parameters, none of these correlations turned out to be significant. More research is needed to draw any conclusion about the relationship between periodontitis and hypercholesterolemia and hypertriglyceridemia.

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