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Br J Oral Maxillofac Surg. 2009 Jan;47(1):62-4. doi: 10.1016/j.bjoms.2008.06.015. Epub 2008 Oct 30.

Multicentric granular cell tumor: report of a patient with oral and cutaneous lesions.

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  • 1Department of Oral Pathology, School of Dentistry, Federal University of Uberlândia, Brazil.


Granular cell tumor (GCT) is an uncommon benign neoplasm of soft tissue that characteristically affects the oral cavity, with increased frequency in the tongue. In this paper, we report a multicentric GCT affecting a 41-year-old black woman, with nodules in perineum, groin, vulva, tongue and lip. Some of these lesions were surgically resected, but in a six-year follow-up, new primary lesions and recurrences were observed. In addition, the patient opted to do not remove some of these lesions, but there were not significant intercurrences. In view of the present findings, aspects related to clinical presentation, multiplicity, malignant potential, and treatment of GCT are discussed.

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