Display Settings:

Format

Send to:

Choose Destination
See comment in PubMed Commons below
Curr Opin Microbiol. 2008 Dec;11(6):481-7. doi: 10.1016/j.mib.2008.10.007. Epub 2008 Nov 3.

Secondary metabolism: regulation and role in fungal biology.

Author information

  • 1School of Botany, The University of Melbourne, Victoria, 3010, Australia.

Abstract

Filamentous fungi produce a diverse array of secondary metabolites--small molecules that are not necessary for normal growth or development. Secondary metabolites have a tremendous impact on society; some are exploited for their antibiotic and pharmaceutical activities, others are involved in disease interactions with plants or animals. The availability of fungal genome sequences has led to an enhanced effort at identifying biosynthetic genes for these molecules. Genes that regulate production of secondary metabolites have been identified and a link between secondary metabolism, light and sexual/asexual reproduction established. However, the role of secondary metabolites in the fungi that produce them remains a mystery. Many of these fungi live saprophytically in the soil and such molecules may provide protection against other inhabitants in this ecological niche.

PMID:
18973828
[PubMed - indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Icon for Elsevier Science
    Loading ...
    Write to the Help Desk