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Immunity. 2008 Oct 17;29(4):518-20. doi: 10.1016/j.immuni.2008.09.005.

TLR9 turns the tide on Treg cells.

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  • 1School of Biochemistry and Immunology, Trinity College, Dublin 2, Ireland. kingston.mills@tcd.ie

Abstract

In this issue of Immunity, Hall et al. (2008) demonstrate that commensal bacterial DNA can suppress Treg cell conversion via TLR9-mediated activation of lamina propria dendritic cells and thus potentially disrupt intestinal homeostasis.

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PMID:
18957263
[PubMed - indexed for MEDLINE]
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