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Int Orthop. 2009 Oct;33(5):1347-51. doi: 10.1007/s00264-008-0655-3. Epub 2008 Oct 28.

Fusion versus Bryan Cervical Disc in two-level cervical disc disease: a prospective, randomised study.

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  • 1Orthopaedic and Trauma Department, Qilu Hospital of Shandong University, No. 107 Wenhua Xi Road, Jinan, Shandong, 250012, People's Republic of China.


In this prospective study, our aim was to compare the functional results and radiographic outcomes of fusion and Bryan Cervical Disc replacement in the treatment of two-level cervical disc disease. A total of 65 patients with two-level cervical disc disease were randomly assigned to two groups, those operated on with Bryan Cervical Disc replacement (31) and those operated on with anterior cervical fusion with an iliac crest autograft and plate (34). Clinical evaluation was carried out using the visual analogue scale (VAS), the Short Form 36 (SF-36) and the neck disability index (NDI) during a two year follow-up. Radiological evaluation sought evidence of range of motion, stability and subsidence of the prosthesis. Substantial reduction in NDI scores occurred in both groups, with greater percent improvement in the Bryan group (P = 0.023). The arm pain VAS score improvement was substantial in both groups. Bryan artificial cervical disc replacement seems reliable and safe in the treatment of patients with two-level cervical disc disease.

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