Send to

Choose Destination
See comment in PubMed Commons below
Mol Immunol. 2009 Feb;46(5):755-60. doi: 10.1016/j.molimm.2008.09.013. Epub 2008 Oct 26.

Dual role of complement in adipose tissue.

Author information

  • 1Dept. of Infection, Immunity and Inflammation, University of Leicester, University Road, Leicester LE 1 9HN, United Kingdom.


Once thought of as purely the body's chief energy store, adipose tissue and its constituent adipocytes have emerged as both a metabolic entity and an endocrine one. Complement is generally thought of as originating mainly from hepatic synthesis but also from synthesis by the macrophage phagocyte system. This review revisits early descriptions of adipocytic synthesis of complement components and highlights the need of a systematic analysis of the contribution of adipose tissue to systemic inflammation in order to appreciate the immunological activity of this tissue.

[PubMed - indexed for MEDLINE]
PubMed Commons home

PubMed Commons

How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Elsevier Science
    Loading ...
    Write to the Help Desk