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Mol Cell. 2008 Oct 24;32(2):164-6. doi: 10.1016/j.molcel.2008.10.004.

Targeting a TAF to make muscle.

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  • 1Howard Hughes Medical Institute, Programs in Gene Function and Expression and Molecular Medicine, University of Massachusetts Medical School, Worcester, MA 01605, USA.


In a recent issue of Molecular Cell, Deato et al. (2008) elucidate the basis by which the muscle-specific activator MyoD recruits the core transcription machinery to the promoter of a key regulatory gene involved in myogenic differentiation.

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