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J Pediatr. 2008 Nov;153(5):712-5, 715.e1. doi: 10.1016/j.jpeds.2008.05.043.

Infantile hemangiomas: an emerging health issue linked to an increased rate of low birth weight infants.

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  • 1Department of Dermatology and Pediatrics, Medical College of Wisconsin, Milwaukee, WI 53226, USA.


A total of 420 children with infantile hemangioma (IH) were compared with 353 age-matched controls. Using multivariate logistic regression, low birth weight was the most significant risk factor; for every 500-g decrease in birth weight, the risk of IH increased by 40%. A positive family history also increased the risk of IH (33% vs 15% of controls; P < .001).

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