Appl Opt. 2008 Oct 20;47(30):5616-21.

Parallel scan spectral surface plasmon resonance imaging.

Liu L, He Y, Zhang Y, Ma S, Ma H, Guo J.

Source

Laboratory of Optical Imaging and Sensing, Graduate School at Shenzhen, Tsinghua University, Shenzhen, 518055, China. heyh@sz.tsinghua.edu.cn

Abstract

We describe a parallel scan spectral surface plasmon resonance (SPR) imaging technique. We demonstrate experimentally, with a line-shaped light illumination, that an image acquired with an area CCD detector provides both SPR wavelength information and one-dimensional spatial distribution. Thus two-dimensional distribution of the refractive index of the entire sensing plane can be obtained with a one-dimensional optical line parallel scan. The technique offers advantages of both high sensitivity and high throughput, and could have potential applications in biochips analysis.

PMID:: 18936809; [PubMed - indexed for MEDLINE]

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