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Appl Environ Microbiol. 2009 Jan;75(1):257-60. doi: 10.1128/AEM.01400-08. Epub 2008 Oct 17.

Novel cold-adapted alkaline lipase from an intertidal flat metagenome and proposal for a new family of bacterial lipases.

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  • 1Systems Microbiology Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), P.O. Box 115, Yuseong, Daejon 305-333, Republic of Korea.


A new lipase, LipEH166, isolated from an intertidal flat metagenome, showed no amino acid similarity to any known lipolytic enzyme except in the consensus region. This suggested that LipEH166 and its homologues belong to a new family of lipolytic enzymes. Partial characterization indicated that LipEH166 is a novel cold-adapted alkaline lipase.

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