Fertil Steril. 2009 Apr;91(4 Suppl):1516-7. doi: 10.1016/j.fertnstert.2008.07.1782. Epub 2008 Oct 17.

Thrombophilic gene polymorphisms are risk factors for unexplained infertility.

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Pregnancy Success Center and Rinehart Center for Reproductive Medicine, Chicago, Illinois, USA. cbcoulam@aol.com

Abstract

Earlier studies have shown inherited thrombophilia to be a risk factor for recurrent implantation failure, raising the question of whether this risk is related to the underlying cause of unexplained infertility or to the mechanisms involved in the implantation process. When nine thrombophilic gene polymorphisms were compared among 92 women with the diagnosis of unexplained infertility and 60 fertile control women, women with a history of unexplained infertility displayed a higher prevalence of MTHFR C677T polymorphisms than control women.

PMID:: 18930220; [PubMed - indexed for MEDLINE]

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Methylenetetrahydrofolate Reductase (NADPH2)

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Inherited thrombophilia in infertile women: implication in unexplained infertility. [Fertil Steril. 2010]
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Thrombophilic gene polymorphisms are risk factors for unexplained infertility.
Thrombophilic gene polymorphisms are risk factors for unexplained infertility.
Fertil Steril. 2009 Apr ;91(4 Suppl):1516-7. doi: 10.1016/j.fertnstert.2008.07.1782. Epub 2008 Oct 17 .

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