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J Altern Complement Med. 2008 Oct;14(8):1017-25. doi: 10.1089/acm.2008.0115.

Congenital syndromes involving the lungs: pathogenetic models based on chinese medicine theories.

Author information

  • 1Department of Medical Genetics, China Medical University, Shenyang, China. jliling2000@gmail.com

Abstract

BACKGROUND:

Striking similarity seems to exist between the Jing-Luo and Zang-Fu theories of Chinese Medicine (CM) and clinical features of many so-called multiple congenital anomaly/mental retardation syndromes (MCA/MRs), as both may involve multiple organs and/or body systems.

MATERIALS, METHODS, AND RESULTS:

Comparison of MCA/MRs involving the lungs and paths of 5 Jing-Mai traversing the organ has suggested that development of lung and radial ray (embryonic structure that gives rise to radial-side structures of the upper limb, in particular thumb and radius) are closely connected. The Lung Jing-Mai and those traversing the Kidneys may well explain combined malformations involving the lungs, radial ray, and the body's developmental midline. Furthermore, Zang-Fu theories such as "The Lungs rule the skin and body hair," and "The Lungs as a Zang pair with the Large Intestine" also seem to be in keeping with syndromes simultaneously affecting the lungs, colon, and skin. It may be deducible that the Jing-Mai, as described by CM, probably exists, and that the Jing-Mai and Zang-Fu theories have correctly summarized the connections between particular parts of the human body during embryonic development.

CONCLUSIONS:

The CM theories therefore may provide important insights into the pathogenesis of relevant diseases as well as clues for development of new treatment for lung-related diseases.

PMID:
18928390
[PubMed - indexed for MEDLINE]
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