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    Croat Med J. 2008 Oct;49(5):669-73.

    Low grade peritoneal mucinous carcinomatosis associated with human papilloma virus infection: case report.

    Source

    Department of Pathology, Creighton University Medical Center, 601 N 30th St., Omaha, NE 68131, USA. zorangatalica@creighton.edu

    Abstract

    Pseudomyxoma peritonei is a clinical syndrome characterized by peritoneal dissemination of a mucinous tumor with mucinous ascites. The vast majority of the pseudomyxoma peritonei are associated with mucinous neoplasms of the appendix. We describe a case of pseudomyxoma peritonei associated with mucinous adenocarcinoma of the cervix in a 60-year-old woman. The patient developed low grade mucinous peritoneal carcinomatosis 8 years after hysterectomy for cervical adenocarcinoma. No other primary mucinous tumor was identified and peritoneal carcinomatosis tested positive for high-risk human papilloma virus (HPV), showing both integrated and episomal pattern. HPV has been previously associated with development of cervical carcinomas (both squamous and mucinous) but neither has cervical adenocarcinoma nor HPV been implicated in development of pseudomyxoma peritonei. To the best of our knowledge, this is the first description of HPV-associated malignancy presenting as pseudomyxoma peritonei.

    PMID:
    18925701
    [PubMed - indexed for MEDLINE]
    PMCID:
    PMC2582360
    Free PMC Article

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