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1: Genomics. 1991 Jul;10(3):840-1.Links

The gene for the novel vasoactive peptide endothelin 3 (EDN3) is localized to human chromosome 20q13.2-qter.

Rao VV, Löffler C, Hansmann I.

Institut für Humangenetik, Universität Göttingen, Federal Republic of Germany.

Endothelin 3 is a novel vasoactive peptide of unique structure and belongs to the endothelin gene family. Though it mainly functions as a vasoconstrictor/pressor, it plays a major role in a wide variety of other biological functions, possibly as a novel neuropeptide. Studies with human-mouse somatic cell hybrids have suggested that the gene EDN3 is localized on human chromosome 20. We confirmed this localization and regionally mapped the gene to the region 20q13.2-q13.3.

PMID: 1889823 [PubMed - indexed for MEDLINE]