Am J Clin Pathol. 2008 Nov;130(5):754-64.

Histologic assessment and prognostic factors of malignant pleural mesothelioma treated with extrapleural pneumonectomy.

Source

Department of Anatomic Pathology, University of Texas M.D. Anderson Cancer Center, Houston, USA.

Abstract

We studied 56 cases of malignant pleural mesothelioma (MPM) treated with extrapleural pneumonectomy (EPP). The slides from the EPP specimens were reviewed, and tumors were classified with the guidance of the World Health Organization classification of pleural tumors. Agreement between the histologic type from the EPP review and the diagnostic procedure (DP) reports was evaluated. Histologic and clinical parameters were also correlated with clinical outcome. There was a significant disagreement (P = .0001) between the histologic type in the DP reports and the EPP specimen review. The histologic type from the DP was associated with disease-specific survival (DSS); however, the histologic type from the EPP specimen was not associated with survival. Postoperative treatment was associated with DSS and with recurrence-free survival. Our study confirms that in many cases, final histopathologic typing of MPM is influenced by complete surgical resection and that initial biopsy should be carefully weighed in the treatment stratification.

PMID:: 18854268; [PubMed - indexed for MEDLINE]

Free full text

MeSH Terms

LinkOut - more resources

Full Text Sources

Other Literature Sources

COS Scholar Universe

Medical

Supplemental Content

Related citations

The importance of surgical staging in the treatment of malignant pleural mesothelioma. [J Thorac Cardiovasc Surg. 1996]
The importance of surgical staging in the treatment of malignant pleural mesothelioma.
Rusch VW, Venkatraman E. J Thorac Cardiovasc Surg. 1996 Apr; 111(4):815-25; discussion 825-6.
Extrapleural pneumonectomy versus pleurectomy/decortication in the surgical management of malignant pleural mesothelioma: results in 663 patients. [J Thorac Cardiovasc Surg. 2008]
Extrapleural pneumonectomy versus pleurectomy/decortication in the surgical management of malignant pleural mesothelioma: results in 663 patients.
Flores RM, Pass HI, Seshan VE, Dycoco J, Zakowski M, Carbone M, Bains MS, Rusch VW. J Thorac Cardiovasc Surg. 2008 Mar; 135(3):620-6, 626.e1-3. Epub 2008 Feb 14.
Outcome for patients with malignant pleural mesothelioma referred for Trimodality therapy in Western Australia. [J Thorac Oncol. 2009]
Outcome for patients with malignant pleural mesothelioma referred for Trimodality therapy in Western Australia.
Hasani A, Alvarez JM, Wyatt JM, Bydder S, Millward M, Byrne M, Musk AW, Nowak AK. J Thorac Oncol. 2009 Aug; 4(8):1010-6.
Review Surgical options in malignant pleural mesothelioma: extrapleural pneumonectomy or pleurectomy/decortication. [Semin Thorac Cardiovasc Surg. 2009]
Review Surgical options in malignant pleural mesothelioma: extrapleural pneumonectomy or pleurectomy/decortication.
Flores RM. Semin Thorac Cardiovasc Surg. 2009 Summer; 21(2):149-53.
Review Summary of prognostic factors and patient selection for extrapleural pneumonectomy in the treatment of malignant pleural mesothelioma. [Ann Surg Oncol. 2011]
Review Summary of prognostic factors and patient selection for extrapleural pneumonectomy in the treatment of malignant pleural mesothelioma.
Cao C, Yan TD, Bannon PG, McCaughan BC. Ann Surg Oncol. 2011 Oct; 18(10):2973-9. Epub 2011 Apr 22.

See reviews... See all...

Cited by 1 PubMed Central article

Global gene expression profiling of human pleural mesotheliomas: identification of matrix metalloproteinase 14 (MMP-14) as potential tumour target. [PLoS One. 2009]
Global gene expression profiling of human pleural mesotheliomas: identification of matrix metalloproteinase 14 (MMP-14) as potential tumour target.
Crispi S, Calogero RA, Santini M, Mellone P, Vincenzi B, Citro G, Vicidomini G, Fasano S, Meccariello R, Cobellis G, et al. PLoS One. 2009 Sep 15; 4(9):e7016. Epub 2009 Sep 15.

Related information

Related Citations
Calculated set of PubMed citations closely related to the selected article(s) retrieved using a word weight algorithm. Related articles are displayed in ranked order from most to least relevant, with the “linked from” citation displayed first.
Cited in PMC
Full-text articles in the PubMed Central Database that cite the current articles.

Recent activity

Clear Turn Off Turn On

Histologic assessment and prognostic factors of malignant pleural mesothelioma t...
Histologic assessment and prognostic factors of malignant pleural mesothelioma treated with extrapleural pneumonectomy.
Am J Clin Pathol. 2008 Nov ;130(5):754-64.

PubMed
High confidence rule mining for microarray analysis.
High confidence rule mining for microarray analysis.
IEEE/ACM Trans Comput Biol Bioinform. 2007 Oct-Dec ;4(4):611-23.

PubMed
Satisfaction with team midwifery care for low- and high-risk women: a randomized...
Satisfaction with team midwifery care for low- and high-risk women: a randomized controlled trial.
Birth. 2003 Mar ;30(1):1-10.

PubMed
A panel assessment of glaucoma management: modification of existing RAND-like me...
A panel assessment of glaucoma management: modification of existing RAND-like methodology for consensus in ophthalmology. Part I: Methodology and design.
Am J Ophthalmol. 2008 Mar ;145(3):570-574. Epub 2008 Jan 11 .

PubMed
Avian influenza: a new pandemic threat?
Avian influenza: a new pandemic threat?
Mayo Clin Proc. 2004 Apr ;79(4):523-30; quiz 530.

PubMed

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

PubMed

Display Settings:

Send to:

Histologic assessment and prognostic factors of malignant pleural mesothelioma treated with extrapleural pneumonectomy.

Source

Abstract

MeSH Terms

MeSH Terms

LinkOut - more resources

Full Text Sources

Other Literature Sources

Medical

Supplemental Content

Related citations

Cited by 1 PubMed Central article

Related information

Recent activity

Simple NCBI Directory

Getting Started

Resources

Popular

Featured

NCBI Information