Gene. 2009 Feb 15;431(1-2):13-7. Epub 2008 Sep 18.

Biophysical studies with parallel stranded oligoduplex.

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Laboratory 332, School of Life Sciences, Jawaharlal Nehru University, New Delhi-110067, India. pbhattacharya@mail.jnu.ac.in

Abstract

The thermal denaturation profiles of parallel stranded oligoduplexes during UV-spectroscopy and fluorescence spectroscopy, for the first time, were shown to follow the similar patterns as were described for antiparallel stranded oligoduplexes. The B-form structure of these center-bubble-forming oligoduplexes was determined with circular dichroism. Thermodynamic properties were also discussed.

PMID:: 18848977; [PubMed - indexed for MEDLINE]

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