Eur Urol. 2009 Mar;55(3):739-42. Epub 2008 Oct 1.

Retroperitoneal malignant solitary fibrous tumor of the small pelvis causing recurrent hypoglycemia by secretion of insulin-like growth factor 2.

Wagner S, Greco F, Hamza A, Hoda RM, Holzhausen HJ, Fornara P.

Source

Department of Urology and Kidney Transplantation, Martin Luther University, Ernst Grube Str. 40, 06120 Halle, Saale, Germany. sigrid.wagner@medizin.uni-halle.de

Abstract

A 28-yr-old man presented with recurrent reduced consciousness, generalized seizures of unknown etiology, recurrent hypoglycemia, psychomotor retardation, and grade 2 ectasia of the left kidney. Abdominal computed tomography (CT) and positron emission tomography (PET) scans demonstrated a well-circumscribed suprapubic pelvic mass, measuring 18 x 15 x 11 cm, with involvement of para-aortic lymph nodes and dilatation of the left ureter suggestive of an extragonadal testicular tumor. We excised the tumor by laparotomy, and it was confirmed to be a solitary fibrous tumor (SFT). After surgery and R0 tumor resection, the patient had no further evidence of hypoglycemia or of recurrence.

PMID:: 18848386; [PubMed - indexed for MEDLINE]

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Insulin-Like Growth Factor II

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Cited by 2 PubMed Central articles

Retroperitoneal solitary fibrous tumor-induced hypoglycemia associated with high molecular weight insulin-like growth factor II. [Clin Med Res. 2010]
Retroperitoneal solitary fibrous tumor-induced hypoglycemia associated with high molecular weight insulin-like growth factor II.
Yamakawa-Yokota F, Ozaki N, Okajima A, Nishio H, Nagasaka T, Oiso Y. Clin Med Res. 2010 Dec; 8(3-4):159-62. Epub 2010 Sep 17.
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