Format

Send to:

Choose Destination
See comment in PubMed Commons below
Am J Obstet Gynecol. 2009 Feb;200(2):163.e1-5. doi: 10.1016/j.ajog.2008.08.037. Epub 2008 Oct 9.

The frequency of pregnancy and exposure to cytomegalovirus infections among women with a young child in day care.

Author information

  • 1Department of Pediatrics, Medical of College of Virginia Campus, Virginia Commonwealth University School of Medicine, Richmond, VA, USA. bmarshall@mcvh-vcu.edu

Abstract

OBJECTIVE:

The purpose of this study was to determine the frequency of pregnancy and exposure to cytomegalovirus (CMV) among mothers contemplating a possible additional pregnancy and with a child less than 2 years of age in group day care.

STUDY DESIGN:

We performed a prospective observational study that included a demographic questionnaire and serologic and virologic monitoring of mothers and their children in day care.

RESULTS:

Of 60 women, 62% were seronegative and 20% had a child shedding CMV. Of the 60 women, 23 women or 38% (95% CI, 0.27-0.51) became pregnant on average 10 months after enrollment. During pregnancy, 8 or 35% (95% CI, 0.19-0.55) of these pregnant women had a child in day care who shed CMV.

CONCLUSION:

These results illustrate the potential magnitude of the public problem associated with exposure to a silent viral infection during pregnancy. Our data, when extrapolated to the US population, estimate that every 2 years between 31,000 and 168,000 susceptible pregnant women will be exposed to CMV by an infected child.

PMID:
18845286
[PubMed - indexed for MEDLINE]
PMCID:
PMC2662485
Free PMC Article
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Elsevier Science Icon for PubMed Central
    Loading ...
    Write to the Help Desk