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    J Proteome Res. 2008 Nov;7(11):5040-8. Epub 2008 Oct 8.

    Estrogen regulation of proteins in the rat ventromedial nucleus of the hypothalamus.

    Mo B, Callegari E, Telefont M, Renner KJ.

    Department of Biology and Neuroscience Group, University of South Dakota, Vermillion, South Daklota 57069, USA.

    The effects of estradiol (E2) on the expression of proteins in the pars lateralis of the ventromedial nucleus of the hypothalamus (VMNpl) in ovariectomized rats was studied using 2-dimensional gel electrophoresis followed by RPLC-nanoESI-MS/MS. E2 treatment resulted in the up-regulation of 29 identified proteins. Many of these proteins are implicated in the promotion of neuronal plasticity and signaling.

    PMID: 18841879 [PubMed - indexed for MEDLINE]

    PMCID: PMC2633946

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