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    J Assist Reprod Genet. 2008 Sep-Oct;25(9-10):445-52. Epub 2008 Oct 7.

    Effects of men and recipients' age on the reproductive outcome of an oocyte donation program.

    Source

    IVI-Almería, Almería, Spain. eicampos@ivi.es

    Abstract

    PURPOSE:

    The objective of this study was to evaluate the effect of men and recipient age on the reproductive outcome of our oocyte donation program.

    METHODS:

    We retrospectively analyzed 915 cycles, taking into account men and recipient age, separately and together.

    RESULTS:

    The significant cut off value for men and recipients age with incidence in the reproductive outcome was 39 years. Recipient older than 38 years presented a significantly lower pregnancy and implantation rates than others (44.92 vs. 55.75 +/- 1.53%, 25.66 vs. 32.79 +/- 1.64%). If men age was older than 38, a significant reduction in pregnancy and implantation rates was observed, too (46.0 vs. 54.65%, 26.00 +/- 1.52 vs. 32.43 +/- 1.65%). When men and recipient age was analyzed together, a reduction in pregnancy and implantation was detected only if both were older than 38.

    CONCLUSIONS:

    Present study suggests that age has a detrimental effect on the reproductive outcome of oocyte donation cycles when both men and recipient are > or = 39 years old.

    PMID:
    18839305
    [PubMed - indexed for MEDLINE]
    PMCID:
    PMC2582099
    Free PMC Article

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