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World J Gastroenterol. 2008 Oct 7;14(37):5763-8.

Primary signet ring cell carcinoma of the appendix: a rare case report and our 18-year experience.

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  • 1Department of Internal Medicine, Catholic University, Banpo-dong 505, Seocho-gu, Seoul 137-701, South Korea.

Abstract

Primary adenocarcinoma of the appendix is a rare malignancy that constitutes < 0.5% of all gastrointestinal neoplasms. Moreover, primary signet ring cell carcinoma of the appendix is an exceedingly rare entity. We have encountered 15 cases of primary appendiceal cancer among 3389 patients who underwent appendectomy over the past 18 years. In the present report, we describe a rare case of primary signet ring cell carcinoma of the appendix with ovarian metastases and unresectable peritoneal dissemination occurring in a 67-year-old female patient. She underwent appendectomy and bilateral salpingo-oophorectomy with a laparoscopy procedure. She then received palliative systemic chemotherapy with 12 cycles of oxaliplatin, 5-flurorouracil, and leucovorin (FOLFOX-4). The patient currently is well without progression of disease 12 mo after beginning chemotherapy.

PMID:
18837098
[PubMed - indexed for MEDLINE]
PMCID:
PMC2748216
Free PMC Article

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