J Int Med Res. 2008 Sep-Oct;36(5):1117-22.

The views of doctors on registration trials in a Japanese rural area: a survey of medical institutions registered to the Tokushima Network for Clinical Trials.

Yanagawa H, Irahara M, Kawashima S, Kagawa S; Tokushima Network for Clinical Trials.

Source

Clinical Trial Centre for Developmental Therapeutics, Tokushima University Hospital, Tokushima, Japan. niseko@clin.med.tokushima-u.ac.jp

Abstract

Tokushima University Hospital has established the Tokushima Network for Clinical Trials (TNCT) to promote clinical trials in the area in collaboration with the Tokushima Medical Association. The present study investigated the views of doctors towards registration trials in the TNCT. A questionnaire was provided to 49 clinics/hospitals registered to the TNCT in 2006 and 38 (78%) responded. It revealed that 48% of doctors were aware of registration trials and 87% were favourable towards participating as investigators in them. They considered close contact with developmental drugs, advancement of therapy and the opportunity to learn about state-of-the-art treatment as benefits of participation. The main areas of difficulty included management of adverse reactions and patients' refusal to take part. Many doctors wanted more opportunity to learn about trial-related issues such as regulations. The survey indicates that the TNCT needs to develop the infrastructure and enlighten participants to promote registration trials in this rural regional area.

PMID:: 18831909; [PubMed - indexed for MEDLINE]

Publication Types, MeSH Terms

Publication Types

Research Support, Non-U.S. Gov't

MeSH Terms

LinkOut - more resources

Full Text Sources

Ingenta plc

Other Literature Sources

Labome Researcher Resource - ExactAntigen/Labome

Medical

Supplemental Content

Save items

Related citations in PubMed

Clinical trials for drug approval: a pilot study of the view of doctors at Tokushima University Hospital. [J Med Invest. 2006]
Clinical trials for drug approval: a pilot study of the view of doctors at Tokushima University Hospital.
Yanagawa H, Nishiya M, Miyamoto T, Shikishima M, Imura M, Nakanishi R, Ariuchi K, Akaishi A, Takai S, Abe S, et al. J Med Invest. 2006 Aug; 53(3-4):292-6.
View of physicians on and barriers to patient enrollment in a multicenter clinical trial: experience in a Japanese rural area. [Int Arch Med. 2010]
View of physicians on and barriers to patient enrollment in a multicenter clinical trial: experience in a Japanese rural area.
Yanagawa H, Kishuku M, Akaike M, Azuma H, Irahara M. Int Arch Med. 2010 Jun 4; 3:7. Epub 2010 Jun 4.
Consenting of the vulnerable: the informed consent procedure in advanced cancer patients in Mexico. [BMC Med Ethics. 2006]
Consenting of the vulnerable: the informed consent procedure in advanced cancer patients in Mexico.
Verástegui EL. BMC Med Ethics. 2006 Dec 13; 7:E13. Epub 2006 Dec 13.
Review Evaluation of primary care practice in the University of Tokushima. [J Med Invest. 2009]
Review Evaluation of primary care practice in the University of Tokushima.
Tani K, Iwasaki T, Kawaminami S, Yuasa S, Saijo A. J Med Invest. 2009 Aug; 56(3-4):81-7.
Review [Informed consent in connection with autopsy and sending out discharge notes. A questionnaire study]. [Ugeskr Laeger. 1999]
Review [Informed consent in connection with autopsy and sending out discharge notes. A questionnaire study].
Jensen RB, Thomsen OO. Ugeskr Laeger. 1999 Oct 4; 161(40):5531-6.

See reviews... See all...

Cited by 1 PubMed Central article

Role of clinical research coordinators in promoting clinical trials of drugs for surgical patients. [Int Arch Med. 2008]
Role of clinical research coordinators in promoting clinical trials of drugs for surgical patients.
Yanagawa H, Akaishi A, Miyamoto T, Takai S, Nakanishi R, Irahara M. Int Arch Med. 2008 Dec 10; 1(1):26. Epub 2008 Dec 10.

Related information

Related Citations
Calculated set of PubMed citations closely related to the selected article(s) retrieved using a word weight algorithm. Related articles are displayed in ranked order from most to least relevant, with the “linked from” citation displayed first.
Cited in PMC
Full-text articles in the PubMed Central Database that cite the current articles.

Recent activity

Clear Turn Off Turn On

The views of doctors on registration trials in a Japanese rural area: a survey o...
The views of doctors on registration trials in a Japanese rural area: a survey of medical institutions registered to the Tokushima Network for Clinical Trials.
J Int Med Res. 2008 Sep-Oct ;36(5):1117-22.

PubMed
Reduction in cerebral atrophy associated with ethyl-eicosapentaenoic acid treatm...
Reduction in cerebral atrophy associated with ethyl-eicosapentaenoic acid treatment in patients with Huntington's disease.
J Int Med Res. 2008 Sep-Oct ;36(5):896-905.

PubMed
Obesity and osteoarthritis in knee, hip and/or hand: an epidemiological study in...
Obesity and osteoarthritis in knee, hip and/or hand: an epidemiological study in the general population with 10 years follow-up.
BMC Musculoskelet Disord. 2008 Oct 2 ;9:132.

PubMed
Oxidative stress, lens gap junctions, and cataracts.
Oxidative stress, lens gap junctions, and cataracts.
Antioxid Redox Signal. 2009 Feb ;11(2):339-53.

PubMed
Long-term outcomes and prognostic factors in pediatric patients with severe trau...
Long-term outcomes and prognostic factors in pediatric patients with severe traumatic brain injury and elevated intracranial pressure.
J Neurosurg Pediatr. 2008 Oct ;2(4):240-9.

PubMed

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

PubMed

Result Filters

Display Settings:

Send to: