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1: Int Semin Surg Oncol. 2008 Oct 2;5:22.Click here to read Click here to read Links

Adjacent thoracic lymph node metastases originating from two separate primary cancers: case report.

El-Gendy KA, Atkin GK, Brightwell RE, Richman P, Livingstone JI.

Department of Biosurgery and Surgical Technology, Imperial College London, London, UK. r.brightwell04@imperial.ac.uk.

ABSTRACT: Reported is an unusual case of adjacent thoracic lymph nodes demonstrating metastases from two different primary malignancies. A 51 year-old woman with a previous history of bilateral breast cancer underwent a radical gastro-oesophagectomy for adenocarcinoma of the lower third of the oesophagus. The resection specimen demonstrated breast and oesophageal metastases in adjacent thoracic lymph nodes. Mechanisms for this phenomenon, including the known local immune suppression on lymphoid cells by oesophageal carcinoma cells, are discussed.

PMID: 18831741 [PubMed - in process]

PMCID: PMC2569954