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    Clin Infect Dis. 2008 Nov 1;47(9):1226-30.

    Drug toxicity, HIV progression, or comorbidity of aging: does tipranavir use increase the risk of intracranial hemorrhage?

    Justice AC, Zingmond DS, Gordon KS, Fultz SL, Goulet JL, King JT Jr, Bravata DM, Valdez H, Kraft M, Mattocks KM; Veterans Aging Cohort Study Project Team.

    Veterans Affairs Connecticut Healthcare System, West Haven, Connecticut 06516, USA.

    The US Food and Drug Administration has issued a warning that tipranavir may be associated with increased risk of intracranial hemorrhage. We studied 2 large cohorts to estimate the background rate of intracranial hemorrhage and compared it with rates reported among persons who had been exposed to tipranavir.

    PMID: 18831696 [PubMed - indexed for MEDLINE]

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    Patient drug information

    • Tipranavir (Aptivus®)

      Tipranavir is used with ritonavir (Norvir) and at least 2 other medications to treat human immunodeficiency virus (HIV). Tipranavir is in a class of medications called protease inhibitors. It works by slowing the spread ...

    • Source: AHFS Consumer Medication Information

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