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Genome Biol. 2008;9(9):233. doi: 10.1186/gb-2008-9-9-233. Epub 2008 Sep 16.

Transcriptional (dys)regulation and aging in Caenorhabditis elegans.

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  • 1Department of Molecular, Yale University, New Haven, CT 06520, USA.

Abstract

A circuit of transcription factors has been discovered in Caenorhabditis elegans that could provide a link between laboratory-defined intracellular 'longevity pathways', gene dysregulation and the process of normal aging.

PMID:
18828877
[PubMed - indexed for MEDLINE]
PMCID:
PMC2592707
Free PMC Article

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