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1: J Biol. 2008 Sep 16;7(7):23. [Epub ahead of print]Click here to read Links

Appetite for reproduction: dietary restriction, aging and the mammalian gonad.

Nalam RL, Pletcher SD, Matzuk MM.

Department of Pathology, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA. mmatzuk@bcm.edu.

ABSTRACT: The major physiologic theory of aging, the disposable soma theory, links dietary restriction (DR), also known as calorie or food restriction, to prolonged lifespan and makes specific predictions about the effects of aging and DR on reproduction. A recent study in BMC Biology profiling the effects of aging and DR on gonadal gene expression provides novel molecular evidence that has a significant impact on this theory of aging.

PMID: 18828876 [PubMed - as supplied by publisher]