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Nat Prod Rep. 2008 Oct;25(5):854-61. doi: 10.1039/b805700c. Epub 2008 Jul 10.

Tedanolide and the evolution of polyketide inhibitors of eukaryotic protein synthesis.

Author information

  • Department of Chemistry & Biochemistry and the Walther Cancer Research Center, University of Notre Dame, Notre Dame, IN 46556-5670, USA. taylor.61@nd.edu

Abstract

This Highlight covers the chemical and biological studies regarding a set of polyketide inhibitors of eukaryotic protein synthesis related to the marine-derived cytotoxic agent tedanolide.

PMID:
18820754
[PubMed - indexed for MEDLINE]
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