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PLoS Biol. 2008 Sep 30;6(9):e243. doi: 10.1371/journal.pbio.0060243. Epub 2008 Sep 23.

Of mice and men, and chandeliers.

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  • 1the Howard Hughes Medical Institute, Department of Biological Sciences, Columbia University, New York, New York, United States of America.


How does the human neocortex reliably propagate information through neural circuits? One mechanism appears to involve relying on strong connections from pyramidal neurons to interneurons and a depolarizing action of cortical chandelier cells.

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