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    Br J Cancer. 2008 Nov 4;99(9):1534-8. Epub 2008 Sep 23.

    Coffee intake and CYP1A2*1F genotype predict breast volume in young women: implications for breast cancer.

    Jernström H, Henningson M, Johansson U, Olsson H.

    Department of Oncology, Clinical Sciences, Lund University, Barngatan 2B, SE-221 85 Lund, Sweden. helena.jernstrom@med.lu.se

    As breast volume may be associated with heart cancer risk, we studied the relationship between breast volume, CYP1A2*1F and coffee intake. Among healthy premenopausal non-hormone users, 3+ cups per day was associated with lower volume only in C-allele carriers (P(interaction)=0.02), which is consistent with reports that coffee protects only C-allele carriers against breast cancer.

    PMID: 18813311 [PubMed - indexed for MEDLINE]

    PMCID: 2579678

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