Exp Oncol. 2008 Sep;30(3):181-9.

Image-based evaluation of tumor response to treatment: where is radiology today?

Kharuzhyk S, Fabel M, von Tengg-Kobligk H, Kauczor HU.

Source

N.N. Alexandrov National Cancer Center of Belarus, Minsk, Belarus. skharuzhyk@nld.by

Abstract

Oncological patient care requires long term follow-up in order to estimate effectiveness of existing and new treatment choices. Image-based assessment of whole body tumour burden is commonly used for that purpose. The WHO response criteria were established in 1979 proposing bi-dimensional tumor measurements. New RECIST guidelines appeared in 2000 relying on only the longest diameter (uni-dimensional) measurements. Obviously, a change in tumour size is only one potential surrogate for therapy response which not necessarily reflects the biologic activity of the tumour or the effect of particular therapy. Thus, the evaluation of biological, metabolic or molecular properties of a tumor and its changes might be an attractive means to assess the response to therapy sensitively and early.

PMID:: 18806739; [PubMed - indexed for MEDLINE]

Publication Types, MeSH Terms, Substances

Publication Types

MeSH Terms

Substances

LinkOut - more resources

Full Text Sources

MORION LLC

Other Literature Sources

Labome Researcher Resource - ExactAntigen/Labome

Medical

Supplemental Content

Related citations

A statistical simulation study finds discordance between WHO criteria and RECIST guideline. [J Clin Epidemiol. 2004]
A statistical simulation study finds discordance between WHO criteria and RECIST guideline.
Mazumdar M, Smith A, Schwartz LH. J Clin Epidemiol. 2004 Apr; 57(4):358-65.
Review RECIST revised: implications for the radiologist. A review article on the modified RECIST guideline. [Eur Radiol. 2010]
Review RECIST revised: implications for the radiologist. A review article on the modified RECIST guideline.
van Persijn van Meerten EL, Gelderblom H, Bloem JL. Eur Radiol. 2010 Jun; 20(6):1456-67. Epub 2009 Dec 22.
Review [New imaging strategies for monitoring molecular pharmacotherapy of GIST]. [Radiologe. 2008]
Review [New imaging strategies for monitoring molecular pharmacotherapy of GIST].
Berger F, Reiser M. Radiologe. 2008 Sep; 48(9):832-8.
Review RECIST revisited: a review of validation studies on tumour assessment. [Eur J Cancer. 2006]
Review RECIST revisited: a review of validation studies on tumour assessment.
Therasse P, Eisenhauer EA, Verweij J. Eur J Cancer. 2006 May; 42(8):1031-9. Epub 2006 Apr 17.
Review Efaproxiral: GSJ 61, JP 4, KDD 86, RS 4, RSR 13. [Drugs R D. 2005]
Review Efaproxiral: GSJ 61, JP 4, KDD 86, RS 4, RSR 13.
. Drugs R D. 2005; 6(3):178-85.

See reviews... See all...

Cited by 1 PubMed Central article

Hepatocellular carcinoma: consensus recommendations of the National Cancer Institute Clinical Trials Planning Meeting. [J Clin Oncol. 2010]
Hepatocellular carcinoma: consensus recommendations of the National Cancer Institute Clinical Trials Planning Meeting.
Thomas MB, Jaffe D, Choti MM, Belghiti J, Curley S, Fong Y, Gores G, Kerlan R, Merle P, O'Neil B, et al. J Clin Oncol. 2010 Sep 1; 28(25):3994-4005. Epub 2010 Aug 2.

Related information

Related Citations
Calculated set of PubMed citations closely related to the selected article(s) retrieved using a word weight algorithm. Related articles are displayed in ranked order from most to least relevant, with the “linked from” citation displayed first.
Cited in PMC
Full-text articles in the PubMed Central Database that cite the current articles.

Recent activity

Clear Turn Off Turn On

Image-based evaluation of tumor response to treatment: where is radiology today?
Image-based evaluation of tumor response to treatment: where is radiology today?
Exp Oncol. 2008 Sep ;30(3):181-9.

PubMed
Gum arabic establishes prebiotic functionality in healthy human volunteers in a ...
Gum arabic establishes prebiotic functionality in healthy human volunteers in a dose-dependent manner.
Br J Nutr. 2008 Dec ;100(6):1269-75. Epub 2008 May 9 .

PubMed
Perinatal hepatitis B prevention: adapting Public Health Services to meet the ch...
Perinatal hepatitis B prevention: adapting Public Health Services to meet the changing needs of a diverse community.
Public Health Rep. 2009 May-Jun ;124(3):454-7.

PubMed
Food allergy knowledge, attitudes, and beliefs in the United States.
Food allergy knowledge, attitudes, and beliefs in the United States.
Ann Allergy Asthma Immunol. 2009 Jul ;103(1):43-50.

PubMed
Idiopathic central precocious puberty in girls: presentation factors.
Idiopathic central precocious puberty in girls: presentation factors.
BMC Pediatr. 2008 Jul 4 ;8:27.

PubMed

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

PubMed

Display Settings:

Send to: