Am J Dermatopathol. 2008 Oct;30(5):451-4.

Vitiligo-like primary melanoma.

Lugo-Somolinos A, Sánchez JL, Garcia ME.

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Department of Dermatology, University of North Carolina-Chapel Hill, Chapel Hill, NC, USA.

Abstract

Depigmented or hypopigmented macules and patches have been described in association to primary and metastatic melanoma. Primary melanoma presenting at the onset as a vitiliginous patch without histopathological evidence of regression seems to be a rare event. We report 2 patients with melanoma in situ that expressed clinically as vitiligo-like patches and review the possible immunologic mechanisms responsible for this unusual presentation.

PMID:: 18806487; [PubMed - indexed for MEDLINE]

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Vitiligo-like primary melanoma.

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