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Dev Cell. 2008 Sep;15(3):331-2. doi: 10.1016/j.devcel.2008.08.009.

Probing meiotic recombination decisions.

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  • 1Molecular Biology Program, Memorial Sloan-Kettering Cancer Center, New York, NY 10065, USA.


Meiotic recombination promotes genetic variation by mixing parental alleles. Two recent studies, one in this issue of Developmental Cell, have applied microarray-based methods that allow analysis of nearly all of the recombination events occurring in a single meiosis. These data provide insights into the molecular "decisions" that control the outcome of the recombination process.

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