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Fungal Genet Biol. 2009 Mar;46 Suppl 1:S45-52. doi: 10.1016/j.fgb.2008.08.008. Epub 2008 Sep 3.

A survey of nonribosomal peptide synthetase (NRPS) genes in Aspergillus nidulans.

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  • 1Technical University Berlin, Institute of Chemistry OE2, Franklinstr. 29, 10587 Berlin, Germany. doehren@chem.tu-berlin.de

Abstract

The genome of Aspergillus nidulans carries 27 genes encoding nonribosomal peptide synthetase (NRPS) structures, although only five of these forming peptides and amino acid containing metabolites have been identified so far. This manuscript describes domain structures, substrate binding pockets and related genes and gene clusters and summarizes our current state of product prediction of fungal NRPS systems.

PMID:
18804170
[PubMed - indexed for MEDLINE]
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