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1: J Pediatr Hematol Oncol. 2008 Jul;30(7):553-7. Links

Paraspinal synovial sarcoma as an unusual postradiation complication in pediatric abdominal neuroblastoma.

Mullah-Ali A, Ramsay JA, Bourgeois JM, Hodson I, Macdonald P, Midia M, Portwine C.

Departments of Pediatric Hematology/Oncology, Division of Pediatrics, McMaster University, Hamilton, Ontario, Canada. mullah_ali@hotmail.com

SUMMARY: The development of a soft-tissue sarcoma is an infrequent but well-known long-term complication of radiotherapy. Malignant fibrous histiocytomas, extraskeletal osteosarcomas, fibrosarcomas, malignant peripheral nerve sheath tumors, and angiosarcomas are most frequently encountered. Radiation-associated synovial sarcomas are uncommon and exceedingly rare in pediatric patients. We report an unusual case of paraspinal synovial sarcoma presenting in an adolescent female 13 years after radiation therapy for her neuroblastoma.

PMID: 18797206 [PubMed - indexed for MEDLINE]

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