Format

Send to

Choose Destination
See comment in PubMed Commons below
Proc Biol Sci. 2009 Jan 7;276(1654):145-51. doi: 10.1098/rspb.2008.1157.

Strain-specific priming of resistance in the red flour beetle, Tribolium castaneum.

Author information

  • 1Institute for Integrative Biology, Experimental Ecology, Universitätsstrasse 16, ETH-Zentrum, 8092 Zürich, Switzerland. olivia.roth@env.ethz.ch

Abstract

As invertebrates lack the molecular machinery employed by the vertebrate adaptive immune system, it was thought that they consequently lack the ability to produce lasting and specific immunity. However, in recent years, it has been demonstrated that the immune defence of invertebrates is by far more complicated and specific than previously envisioned. Lasting immunity following an initial exposure that proves protection on a secondary exposure has been shown in several species of invertebrates. This phenomenon has become known as immune priming. In the cases where it is explicitly tested, this priming can also be highly specific. In this study, we used survival assays to test for specific priming of resistance in the red flour beetle, Tribolium castaneum, using bacteria of different degrees of relatedness. Our results suggest an unexpected degree of specificity that even allows for differentiation between different strains of the same bacterium. However, our findings also demonstrate that specific priming of resistance in insects may not be ubiquitous across all bacteria.

[PubMed - indexed for MEDLINE]
Free PMC Article
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for HighWire Icon for PubMed Central
    Loading ...
    Write to the Help Desk