Multi-spectral angular domain optical imaging in biological tissues using diode laser sources

Opt Express. 2008 Sep 15;16(19):14456-68. doi: 10.1364/oe.16.014456.

Abstract

Angular Domain Imaging (ADI) employs micromachined angular filter to detect non-scattered photons that pass through the micro-scale tunnels unattenuated while scattered photons are rejected. This paper describes the construction of an ADI system utilizing diode lasers at three different wavelengths in the range of the red and near infrared spectrum. Experiments are performed to verify the feasibility of ADI at multi-wavelengths. ADI results of chicken breast as a biological scattering medium are presented for different thicknesses. A spatial resolution of <0.5 mm is achieved with 5 mm thick chicken breast using a 975 nm diode laser source.

MeSH terms

  • Diagnostic Imaging / instrumentation*
  • Equipment Design
  • Equipment Failure Analysis
  • Lasers, Semiconductor*
  • Nephelometry and Turbidimetry / instrumentation*
  • Spectrum Analysis / instrumentation*
  • Tomography, Optical / instrumentation*